Five of the 12 NBA teams in action on Wednesday's NBA schedule are playing on the second night of a back-to-back. This includes many of the league's top scorers such as Luka Doncic, Donovan Mitchell and Anthony Edwards. NBA prop bettors would be well-served in observing how a player performs on a back-to-back before making any player props on sites like PrizePicks. For example, Doncic leads the league with 34.5 points per game, but he's averaging just 29.3 points in his six games with no rest in between.

Some sportsbooks may not be as sophisticated when it comes to setting NBA prop lines and not taking things like this into account. Doncic has a points total of 33.5 as the Mavs play in Toronto tonight after a crushing last-second defeat in Cleveland on Tuesday night. What other player trends should you be aware of before betting any Wednesday NBA player props? Before making any NBA prop picks on sites like PrizePicks for Wednesday, be sure to check out the NBA predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model enters Week 19 of the 2023-24 NBA season on a sizzling 63-39 roll on all top-rated NBA picks this season, returning more than $2,200. Anyone following it has seen huge returns.

For Wednesday's NBA schedule, the model has locked in its NBA best bets. You can only see the model's NBA prop picks at SportsLine

Top NBA prop bet for Wednesday

After simulating every game on Wednesday's NBA schedule 10,000 times, the model is picking Under 12.5 rebounds for Nuggets center Nikola Jokic at -111 odds. Denver hosts the Kings for their third matchup over the last three weeks. The teams also met on both Feb. 9 and Feb. 14 in which Jokic combined to barely hit what's his total for Wednesday. He had 13 total rebounds across those games, logging eight in the Feb. 9 loss and then five in the Valentine's day defeat.

Over his last five games against Sacramento, Jokic has gone Under 12.5 rebounds four times. He hasn't just gone Under 12.5, but he's had single-digit boards in four of those five games. As a team, the Kings haven't been outrebounded by an opponent in seven straight games, and Domantas Sabonis leads the NBA with 13.2 rebounds per game. His presence doesn't make things easy for Jokic on the glass, and all of these trends have the model backing Under 12.5 rebounds for Jokic. You can see which other NBA picks to back here.

All NBA prop bets for Wednesday's NBA schedule

7:30 p.m. ET: Pelicans vs. Pacers
See Pacers vs. Pelicans props here

7:30 p.m. ET: Mavericks vs. Raptors
See Raptors vs. Mavericks props here

8 p.m. ET: Grizzlies vs. Timberwolves
See Timberwolves vs. Grizzlies props here

8 p.m. ET: Cavaliers vs. Bulls
See Bulls vs. Cavaliers props here

9 p.m. ET: Kings vs. Nuggets
See Nuggets vs. Kings props here

10 p.m. ET Lakers vs. Clippers
See Clippers vs. Lakers props here

How to make NBA prop picks for Wednesday

The model has simulated every NBA game 10,000 times and has some surprising projections for Wednesday's schedule. You can only see the model's NBA best bets and SGP picks at SportsLine

Which NBA prop picks should you target on Wednesday? Visit SportsLine now to see the NBA best bets from an advanced model that is on a 63-39 run on top-rated NBA picks, and find out.