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The Jacksonville Jaguars (1-4) and Chicago Bears (3-2) will meet in the 2024 NFL London Games to get the Week 6 NFL Sunday schedule underway. The Bears are looking to keep their two-game win streak going. Last week, Chicago blew out the Carolina Panthers, 36-10. Meanwhile, the Jaguars finally got in the win column last week after toppling the Indianapolis Colts, 37-34, in an AFC South tilt.

Kickoff from Tottenham Hotspur Stadium in London is set for 9:30 a.m. ET. Jacksonville is a 1-point favorite in the latest Jaguars vs. Bears odds from SportsLine Consensus, a two-point swing from the opener, while the over/under for total points scored is 44.5. The Jaguars are -113 money-line favorites (risk $113 to win $100), while the Bears are -108 underdogs. Before locking in any Bears vs. Jaguars picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up!

Now, the model has simulated Jags vs. Bears 10,000 times and just revealed its coveted NFL picks and Jaguars vs. Bears betting predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and NFL betting lines for the spreadmoney line and over/under for Bears vs. Jags:

  • Jaguars vs. Bears spread: Jacksonville -1
  • Jaguars vs. Bears over/under: 44.5 points
  • Jaguars vs. Bears money line: Chicago -108, Jacksonville -113
  • JAX: Jaguars have hit the 2Q Over in seven of their last 10 away games
  • CHI: Bears have scored first in eight of their last 10 games
  • Jaguars vs. Bears picks: See picks at SportsLine
  • Jaguars vs. Bears streaming: FuboTV (Try for free)

Why the Jaguars can cover

Rookie receiver Brian Thomas Jr. has already become the No. 1 option in Jacksonville's offense. Thomas uses his speed to stretch the field and provides a big-play threat. The LSU product is sixth in the NFL in receiving yards (397) and tied for sixth in receiving touchdowns (6). In the win over the Colts, he had five catches for 122 yards and one touchdown.

Running back Tank Bigsby has plenty of physicality and explosiveness that creates problems for defenses. The Auburn product has 273 rushing yards, two touchdowns and averages eight yards per carry. He's already rushed for 70-plus yards three times in 2024. In his last outing, Bigsby had 101 rushing yards and two scores. See who to back at SportsLine.

Why the Bears can cover

Quarterback Caleb Williams has settled in and is doing a better job getting the ball into the hands of his playmakers. The USC product has thrown for 1,091 yards and five passing touchdowns this season. He has thrown for 300-plus yards in two of his last three games. In his last outing, Williams went 20-of-29 for 304 yards and two passing touchdowns.

Receiver DJ Moore is an explosive pass-catcher who can be dangerous after the catch. The 27-year-old has 27 receptions for 294 yards and three touchdowns this season. In the backfield, running D'Andre Swift has compiled 120-plus scrimmage yards in the past two weeks. Last Sunday, Swift had 73 rushing yards, 47 receiving yards and one score. See who to back at SportsLine.

How to make Jaguars vs. Bears picks

SportsLine's model is leaning Over on the total, projecting the teams to combine for 45 points. The model also says one side of the spread cashes in well over 50% of simulations. Head to SportsLine to see its NFL picks

So who wins Jaguars vs. Bears in the second 2024 NFL London Game, and which side of the spread cashes well over 50% of the time? Visit SportsLine now to see which side of the Jaguars vs. Bears spread to back, all from the model that has returned well over $7,000 on top-rated NFL picks, and find out.