The Lions placed O'Connor (knee) on injured reserve Friday.
O'Connor didn't practice at all last week and missed Sunday's game against Washington. He was unable to return to practice this week and has consequently been placed on IR. The veteran defensive end must now miss at least four contests, so he won't be eligible to return until Sunday, Dec. 14 versus the Rams.
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Lions' Malcolm Rodriguez: Could return Week 11
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Rodriguez (knee) is listed as questionable for Sunday's game against the Eagles.
Rodriguez was a full practice participant all week, but he would need to be activated from injured reserve in order to be eligible to play Sunday. The 2022 sixth-rounder is recovering from a torn ACL that he suffered from November of 2024, and his return would strengthen the Lions' depth at linebacker while giving the team another contributor for special teams. Rodriguez logged 43 tackles (27 solo), including 2.0 sacks, one pass defense and one fumble recovery across 10 regular-season games in 2024.
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Lions' Josh Paschal: Not playing Week 11
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Paschal (back) has been ruled out for Sunday's game against the Eagles.
Paschal was limited in practice all week due to a back injury that he's been recovering from since July. He hasn't progressed enough in his recovery to make his 2025 debut Week 11 and will remain on the reserve/non-football injury list. Paschal's next opportunity to play is Week 12 against the Giants on Sunday, Nov. 23.
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Lions' Amik Robertson: Dealing with hamstring injury
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Robertson (hamstring) is listed as questionable for Sunday's game against the Eagles.
Robertson popped up on Thursday's practice report as a limited participant due to a hamstring injury. He's been given the questionable tag for Sunday's road game, and if he joins Terrion Arnold (concussion) on the inactive list, then Rock Ya-Sin, Avonte Maddox and Nick Whiteside would be the top candidates to start at outside corner. Robertson has started in each of the Lions' last five games, and over that span he has accumulated 16 tackles (14 solo), two pass defenses (one interception) and one forced fumble.
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Lions' D.J. Reed: Chance to return Week 11
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Reed (hamstring) is listed as questionable for Sunday's game against the Eagles.
Reed has a chance to return from a five-game absence due to a hamstring injury that caused him to land on injured reserve in early October. He was limited in all three practices during Week 11 prep, and he would have to be activated from injured reserve Saturday in order to be available for Sunday's road game. Reed's return would be timely for the Lions, given that Terrion Arnold (concussion) has been ruled out and Amik Robertson (hamstring) is listed as questionable for Week 11.
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Lions' Marcus Davenport: Could return Week 11
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Davenport (shoulder) is listed as questionable for Sunday's game against the Eagles.
Davenport's 21-day practice window to return from injured reserve opened Wednesday, and he was limited in all three practices during Week 11 prep. He would have to be activated from injured reserve in order to be available to play Sunday.
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Lions' Kerby Joseph: Missing fourth straight game
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Joseph (knee) has been ruled out for Sunday's game against the Eagles.
Joseph has been unable to practice since injuring his knee during the Lions' Week 6 loss to the Chiefs and will miss a fourth consecutive game as a result. Thomas Harper will continue to start at safety alongside Brian Branch for as long as Joseph is out of action. Joseph's next opportunity to play is Week 12 against the Giants on Sunday, Nov. 23.
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Lions' Terrion Arnold: Won't play against Philadelphia
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Arnold (concussion) has been ruled out for Sunday's game against the Eagles.
Arnold entered the league's concussion protocol during the Lions' Week 10 win over the Commanders, which caused him to miss all three practices during Week 11 prep. A return to practice would indicate that he's progressing through the league's protocol, though he would have to be cleared by an independent neurologist in order to play against the Giants in Week 12. Rock Ya-Sin will likely start at outside corner Sunday in Arnold's absence, and Nick Whiteside and Avontae Maddox could also work with the Lions' first-team defense if Amik Robertson (hamstring) is also ruled out.
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Lions' Aidan Hutchinson: Practices in full Thursday
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Hutchinson (elbow) was a full participant in Thursday's practice.
After popping up on Wednesday's injury report with a shoulder injury and failing to practice, Hutchinson returned to business as usual for Thursday's session. With Eric Woodyard of ESPN.com reporting Wednesday that the injury is not severe, the standout edge rusher should be good to go for Sunday's game against the Eagles.
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Lions' Marcus Davenport: Designated to return from IR
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Davenport (pectoral) had his 21-day practice window to return from injured reserve opened Wednesday, Tim Twentyman of the Lions' official site reports.
Davenport has missed the Lions' last seven games while on injured reserve. He has progressed enough in his recovery from a pectoral injury to return to practice Wednesday, during which he was a limited participant. Davenport likely will need to log full practices before the Lions activate him from IR.
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Lions' Josh Paschal: Returns to practice
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Paschal (back) was a limited participant in Detroit's practice Wednesday.
Paschal has been on the reserve/non-football injury list since July but managed to practice for just the second time since getting hurt. If he's able to practice fully either Thursday or Friday, the 26-year-old could be activated ahead of Sunday's matchup against the Eagles.
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Lions' Malcolm Rodriguez: Full participant in practice
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Rodriguez (knee) was a full participant in Detroit's practice Wednesday.
Rodriguez managed to practice fully for the first time since suffering a torn ACL late last season. If the 26-year-old is able to participate in Thursday and Friday's practices as well, he could be activated off the reserve/PUP list ahead of Sunday's matchup versus the Eagles.
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Lions' Terrion Arnold: Remains in concussion protocol
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Arnold (concussion) didn't participate in Detroit's practice Wednesday.
Arnold remains in the league's concussion protocol and will need to clear it before he's eligible to return to the field. If the 22-year-old is unable to play in Sunday's matchup versus the Eagles, Rock Ya-Sin could see increased playing time.
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Lions' Aidan Hutchinson: Pops up on injury report
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Hutchinson (elbow) didn't participate in Detroit's practice Wednesday, Eric Woodyard of ESPN reports.
Hutchinson popped up on the injury report after failing to record any tackles in the Week 10 win over the Commanders. However, the injury isn't expected to be serious, and the 25-year-old said he'll be good to go for Sunday's matchup versus the Eagles.
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Lions' Kerby Joseph: Remains on injury report
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Joseph (knee) didn't participate in Detroit's practice Wednesday.
Joseph remains sidelined after missing the team's last three games with the knee injury he sustained in the Week 6 loss to the Chiefs. If he's unable to return to practice before Sunday's matchup versus the Eagles, Thomas Harper would likely make his fourth consecutive start at safety.
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Lions' D.J. Reed: Returns to practice
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Reed (hamstring) was designated to return from injured reserve Wednesday, Tim Twentyman of the Lions' official site reports.
Reed has been sidelined since Week 5 with the hamstring injury and remains on injured reserve. He managed a limited practice Wednesday, which still leaves his status for a Week 11 showdown with the Eagles on Sunday night in question.
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Lions' Aidan Hutchinson: Quiet outing in win
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Hutchinson didn't record any tackles in Detroit's win versus the Commanders on Sunday.
Hutchinson has now gone without a tackle in two games this season. The 25-year-old will look to have a bounce-back performance and return to his usual level of production during the team's Week 11 matchup versus the Eagles.
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Lions' Alex Anzalone: Productive in win
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Anzalone recorded five tackles (three solo) during Detroit's win over the Commanders on Sunday.
Anzalone's solid season continues, as he's now racked up at least four tackles in all but one game played. The 31-year-old will look to keep producing when the Lions take on the Eagles in Week 11.
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Lions' Jack Campbell: Limited production in win
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Campbell recorded five total tackles (three solo) in Sunday's 44-22 win over Washington.
Campbell wasn't as busy as usual with Detroit separating from the Commanders down the stretch, securing a season-low five stops. The linebacker had registered at least eight tackles in every game prior to entering Week 10. On the year, Campbell has produced 78 total tackles (43 solo), including 4.0 sacks, while also adding a pass defensed, two forced fumbles and a fumble recovery over nine contests.
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Lions' Brian Branch: Strong performance in Week 10
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Branch recorded seven total tackles (four solo), including 1.5 sacks, in Sunday's 44-22 win over the Commanders.
Branch led the team in stops, and he was able to get to Marcus Mariota twice in the contest, logging a full sack in the first quarter before combining with defensive tackle Roy Lopez to sack the quarterback in the third. The safety is now up to 46 total tackles (31 solo), including 2.5 sacks, while also compiling five passes defensed and a forced fumble over eight games this year.